Table 2. Candidate AIPC progression genes.
Chr.1 | Gene2 | In gene3 | Distance from TSS4 | Up or downstream5 | Expression6 | P-value7 | Vector8 | Tissue9 |
---|---|---|---|---|---|---|---|---|
7 | OR2A14 | No | 3546 | Downstream | Over | 0.000145 | γRV | Lung |
8 | FER1L6 | No | 11278 | Upstream | Over | 0.000242 | γRV | Liver |
12 | TAOK3 | Yes | 9210 | Downstream | Over | 0.000657 | γRV | Lung |
1 | MAN1A2 | Yes | 53962 | Downstream | Under | 0.002 | LV | Lung, Liver |
13 | MBNL2 | Yes | 134465 | Downstream | Under | 0.002 | γRV | Lung |
1 | SERBP1 | Yes | 180 | Downstream | Over | 0.008 | γRV | Lung |
8 | PLEKHA2 | Yes | 53671 | Downstream | Under | 0.011 | LV | Lung |
9 | SPTAN1 | Yes | 42111 | Downstream | Under | 0.015 | LV | Lung |
21 | ADAMTS1 | No | 19479 | Upstream | Under | 0.021 | LV | Lung |
5 | SLC30A5 | No | 16882 | Upstream | Over | 0.03 | LV | Lung |
16 | ABCC1 | Yes | 181992 | Downstream | Over | 0.031 | LV | Lung, Liver |
13 | SLC7A1 | Yes | 71506 | Downstream | Over | 0.046 | γRV | Liver |
1 | SLC25A24 | Yes | 44414 | Downstream | Under | 0.049 | γRV | Lung |
1. Chromosome with vector provirus.
2. Gene tagged by vector provirus.
3. Indicates if the vector provirus is within the gene.
4. Vector provirus distance to the transcription start site (TSS).
5. Indicates if the vector provirus is upstream or downstream from the TSS.
6. Expression of the candidate gene in PC patient tissue from Oncomine™ analysis.
7. p-value from Oncomine™ analysis of expression between PC patient tissue and unaffected tissue.
8. Vector type used for insertional mutagenesis.
9. Tissue from which the metastasis was isolated.