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. Author manuscript; available in PMC: 2019 Apr 3.
Published in final edited form as: Structure. 2018 Mar 8;26(4):657–666.e2. doi: 10.1016/j.str.2018.02.006

Figure 1. The theoretical fold space for IMP.

Figure 1

The theoretical fold space of α-helical MPs is computed through the arrangement of helices (A) and the topological insertion of TMHs (B). The theoretical fold (C) and arrangement (D) numbers scale with the number of TMHs. The computed hexagonal grid and the TMHs are represented as circles from a top view (A): systems with more than three TMHs start to have more than one arrangement. The non-redundant arrangement and fold is computed for each number of TMH. An example fold of a five TMH IMP is illustrated in the rainbow diagram (B). The number of folds (C) and TMH arrangements (D) computed for different numbers of TMHs is plotted on a logarithmic scale.