Table 2. Results of the database-guided analysis per disease category.
| Compass result |
Disease category (initial diagnosis)a |
|||||
|---|---|---|---|---|---|---|
| T-ALL | BCP-ALL | AML | MPAL | AUL | Total | |
| Typical T, B, Myeloid | 30 (64%) | 108 (68%) | 393 (75%) | 4 (7%)b | 0 (0%) | 535 |
| T, B or Myeloid with mixed populations <10% | 9 (19%) | 29 (19%) | 75 (14%) | 3 (5%)c | 0 (0%) | 116 |
| T, B or Myeloid with mixed populations ⩾10% | 1 (2%) | 16 (10%) | 30 (6%) | 7 (13%) | 0 (0%) | 55 |
| Atypical | 4 (9%) | 1 (1%) | 1 (0%) | 3 (5%) | 0 (%) | 9 |
| Mixed lineage | 3 (6%) | 4 (3%) | 23 (4%) | 38 (69%) | 1 (100%) | 69 |
| Total | 47 | 158 | 522 | 55 | 1 | 783 |
Abbreviations: AML, acute myeloid leukemia; AUL, acute undifferentiated leukemia; BCP-ALL, B-cell precursor acute lymphoblastic leukemia; MPAL, mixed phenotype acute leukemia; T-ALL, T-cell acute lymphoblastic leukemia.
a
Number of cases and percentages within each disease category.
b
After review: two AML (with aberrant expression of B-cell markers) and two BCP-ALL with weak/doubtful CyMPO.
c
After review: one BCP-ALL with weak/doubtful CyMPO; one case with a major myeloid population and a small MPAL (B/M) population (<10%), one case with a major myeloid population and a small BCP-ALL population (<10%).