Table 1.
Comparison of the OX40 expression statuses and clinicopathologic features of patients in the West China Hospital (WCH) and The Cancer Genome Atlas (TCGA) sets.
| WCH set |
TCGA set |
|||||
|---|---|---|---|---|---|---|
| Characteristic | Low-OX40 expression (n = 180) | High-OX40 expression (n = 136) | P* | Low-OX40 expression (n = 123) | High-OX40 expression (n = 247) | P* |
| Male sex | 147 (82) | 111 (82) | 0.98 | 87 (71) | 162 (66) | 0.32 |
| Age ≥60 years | 53 (29) | 41 (30) | 0.89 | 62 (50) | 131 (53) | 0.63 |
| HBV infection | 124 (82) | 89 (83) | 0.74 | 41 (38) | 63 (27) | 0.05 |
| Serum AFP level >20 ng/ml | 91 (51) | 93 (69) | < 0.01 | 34 (37) | 96 (52) | 0.03 |
| Single tumor | 130 (85) | 97 (78) | 0.15 | NA | NA | |
| Tumor size >5 cm | 54 (46) | 62 (64) | < 0.01 | NA | NA | |
| Vascular invasion | 37 (21) | 60 (44) | < 0.01 | 29 (27) | 79 (39) | 0.03 |
| Poor differentiation | 66 (41) | 56 (44) | 0.61 | 38 (31) | 95 (39) | 0.12 |
| Non-tumor-liver fibrosis† | 106 (74) | 74 (72) | 0.69 | 26 (33) | 52 (39) | 0.40 |
Note: Data are no. of patients (%) unless otherwise indicated.
Abbreviations: HBV, hepatitis B virus; AFP, alpha fetoprotein; NA, not available.
*
P values are from χ2 tests and t tests for categorical and continuous variables, respectively.
†
Ishak score of 5 or 6.