Figure 3.

Relative treatment efficacy for cardiovascular events. Meta-estimates and 95% credible intervals estimates of sex–treatment interactions for each trial as well as the overall sex–treatment interaction for P2Y₁₂ inhibitors. All estimates were obtained from generalised linear models. The overall sex–treatment interaction was estimated in a hierarchical model. Points represent the point estimates, and bars represent the 95% credible intervals. The point-size for each trial is proportional to the inverse of the SE squared for each interaction estimate. The vertices of the diamond indicate the 95% credible intervals for the meta-estimate, which was obtained from the ‘shared’ model. ACS, acute coronary syndrome.