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. Author manuscript; available in PMC: 2018 May 2.
Published in final edited form as: Nature. 2017 Oct 18;551(7678):115–118. doi: 10.1038/nature24057

Extended Data Figure 6. Concentrations of succinate, malate, and citrate in mouse plasma and tissues.

Extended Data Figure 6

Unlike citrate, succinate and malate have substantially higher concentrations in tissues than in the bloodstream, thus making them a suitable readout for the tissue TCA cycle. Data are from the Mouse Multiple Tissue Metabolome Database (http://mmdb.iab.keio.ac.jp). Values are mean ± s.d. (n = 2 mice). Note that the y-axis is a logarithmic scale.