Table 2. The association of TWIST1 gene methylation levels with clinicopathologic characteristics in patients with colorectal neoplasia.
| Methylated TWIST1 (copies) | |||
|---|---|---|---|
| <2.8 | ≥2.8 | P | |
| Age in years (N = 113) | |||
| Median (range) | 67.0 (36–91) | 68.5 (50–91) | 0.3883 |
| Sex (N = 113) | |||
| Male | 50 | 26 | 1.0000 |
| Female | 25 | 12 | |
| Tumor location (N = 113) | |||
| Right | 44 | 23 | 1.0000 |
| Left | 31 | 15 | |
| Tumor size (mm) (N = 113) | |||
| Median (range) | 20.0 (3–80) | 19.0 (2–74) | 0.4132 |
| Tumor type (N = 113) | |||
| Non-advanced adenoma | 16 | 9 | 0.4918 |
| Advanced adenoma | 49 | 21 | |
| Colorectal cancer | 10 | 8 | |
| Stage (N = 18) | |||
| I | 7 | 7 | 0.5968 |
| II | 1 | 0 | |
| III | 2 | 1 | |
| Tumor differentiation (N = 18) | |||
| Well | 7 | 6 | 0.3910 |
| Moderate | 3 | 1 | |
| Poor | 0 | 1 | |