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. 2018 Apr 6;9(26):18069–18083. doi: 10.18632/oncotarget.24725

Figure 6. Functional role of let-7a in barrier dysfunction.

Figure 6

Cell proliferation and cell infiltration ability were investigated with/without the ABC stimulation on the AGS transfected with a let-7a inhibitor, mimic, negative control plasmids. The snail expression (A) as well as MTT cell proliferation (B) and cell infiltration ability (C) were enhanced under the let-7a inhibition, while they were inhibited by the let-7a induction (A) N = 5, (B) P < 0.05, N = 4, Tukey-Kramer test, (C) P < 0.05, N = 4, Tukey-Kramer test, representative photo of cellular infiltration assay).