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. 2018 Apr 6;9(26):18529–18539. doi: 10.18632/oncotarget.24908

Figure 4. Comparison of Colon Lung version 2 (CLv2, white bars) and Oncomine Lung cfDNA (OLcfDNA, grey bars) mutation status of primary mutation positive non-small cell lung cancer (NSCLC) samples.

Figure 4

(A) CLv2 and OLcfDNA results for the 15 primary point mutations showed accordance in 12 cases (7 EGFR point mutation positive, 4 EGFR wildtype, 1 not analyzable (NA)). (B) Assays showed concordant results in 9/10 primary insertion/deletion mutated samples (5 insertion/deletion positive, 4 wildtype). One CLv2 positive sample was wildtype with OLcfDNA assay. (C) In six patients EGFR T790M mutation was detected with both assays with allele frequencies from 0.1% up to 27.1%. Another OLcfDNA EGFR T790M positive samples was not analyzable with CLv2 panel. *EGFR primary and T790M mutation detected.