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. 2018 Apr 3;9(25):17928–17936. doi: 10.18632/oncotarget.24730

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Schematic showing possible mechanism and differential role of CXCR3 in inflammation and colorectal cancer. The differential effects of CXCR3 by reducing peripheral inflammation and lessens Tregs function that enhances Teff function to mediate colorectal cancer.