Table 1. PET Signal in Striatal Regions of Interest.
[18F]FMT Ki | [11C]RAC BPND | [11C]RAC BPND | [11C]RAC BPND | |
---|---|---|---|---|
placebo | methylphenidate | % change | ||
whole striatum | 0.015±0.002 | 2.19±0.18 | 1.99±0.18 | 8.78±4.23 |
dorsal caudate | 0.019±0.002 | 3.02±0.27 | 2.79±0.27 | 7.48±3.78 |
dorsal putamen | 0.024±0.002 | 3.85±0.27 | 3.48±0.33 | 9.63±5.88 |
ventral striatum | 0.018±0.002 | 2.61±0.22 | 2.40±0.24 | 8.12±4.13 |
Values reflect mean±standard deviation. % change was calculated as 100 x ([11C]raclopride placebo-[11C]raclopride methylphenidate)/ [11C]raclopride placebo. [11C]raclopride is abbreviated as [11C]RAC. degrees of freedom=39.