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The Scientific World Journal logoLink to The Scientific World Journal
. 2006 Apr 28;6:412–528. doi: 10.1100/tsw.2006.93

Transplantation: Polyomavirus Nephropathy and the Risk of Specific Immunosuppression Regimens

Christine Wu 1,*, Parmjeet Randhawa 2, Jerry McCauley 1
PMCID: PMC5917340  PMID: 16648908

Abstract

BK virus is ubiquitously present in the latent state in humans, and awareness of the importance of BK polyomavirus is emerging among the kidney transplant community. First discovered in 1971 in the urine of a renal transplant recipient, BK virus nephropathy (BKVN) has come to be recognized as a significant cause of genitourinary disease and potential graft loss in the kidney transplant patient. In this review, we discuss the risk factors, available methods of diagnosis and therapeutic monitoring, and current approaches to therapy of BKVN.

Keywords: polyomavirus, BK virus, BK nephropathy, kidney transplant


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