Skip to main content
Japanese Journal of Cancer Research : Gann logoLink to Japanese Journal of Cancer Research : Gann
. 1988 Oct;79(10):1067–1074. doi: 10.1111/j.1349-7006.1988.tb01528.x

A Case‐Control Study of Gastric Cancer and Diet in Northern Kyushu, Japan

Suminori Kono 1,, Masato Ikeda 2, Shinkan Tokudome 3, Masanori Kuratsune 4
PMCID: PMC5917639  PMID: 3143695

Abstract

A case‐control study of gastric cancer was done in a rural area of northern Kyushu, Japan, in relation to dietary habits especially focusing on the relationship with the consumption of broiled fish. The study was based upon 139 cases of newly diagnosed gastric cancer at a single institution, 2,574‐ hospital controls and 278 controls sampled randomly from the residents of the study area (with sex and year of birth matched). No association was observed between the consumption of broiled fish and gastric cancer risk whether three types of broiled fish (raw fish, dried fish and salted fish) were analyzed separately or as a single category. However, consistently in the comparisons with both sets of controls, the risk of gastric cancer was inversely related with the consumption of fruits and positively associated with cigarette smoking. A decreased risk of gastric cancer was also noted among those with high consumption of green tea (10 or more cups per day).

Keywords: Gastric cancer, Diet, Case‐control study

Full Text

The Full Text of this article is available as a PDF (391.8 KB).

References

  • 1. ) Haenszel , W. and Correa , P.Development in the epidemiology of stomach cancer over the past decade . Cancer Res. , 35 , 3452 – 3459 ( 1975. ). [PubMed] [Google Scholar]
  • 2. ) Nomura , A.Stomach . In “ Cancer Epidemiology and Prevention ,” ed. Schottenfeld D. and Fraumeni J. F., Jr. , pp. 624 – 637 ( 1982. ). W. B. Saunders; , Philadelphia . [Google Scholar]
  • 3. ) Nagao , M. , Honda , M. , Seino , Y. , Yahagi , T. , Kawachi , T. and Sugimura , T.Mutagenicities of smoke condensates and the charred surface of fish and meat . Cancer Lett. , 2 , 221 – 226 ( 1977. ). [DOI] [PubMed] [Google Scholar]
  • 4. ) Nagao , M. , Honda , M. , Seino , Y. , Yahagi , T. , Kawachi , T. and Sugimura , T.Mutagenicities of protein pyrolysate . Cancer Lett. , 2 , 335 – 340 ( 1977. ). [DOI] [PubMed] [Google Scholar]
  • 5. ) Kasai , H. , Yamaizumi , Z. , Wakabayashi , K. , Nagao , M. , Sugimura , T. , Yokoyama , S. , Miyazawa , T. , Spingarn , N. E. , Weisburger , J. H. and Nishimura , S.Novel mutagens produced by broiling fish under normal conditions . Proc. Jpn. Acad. , 56B , 278 – 283 ( 1980. ). [Google Scholar]
  • 6. ) Ikeda , M. , Yoshimoto , K. , Yoshimura , T. , Kono , S. , Kato , H. and Kuratsune , M.A cohort study on the possible association between broiled fish intake and cancer . Gann , 74 , 640 – 648 ( 1983. ). [PubMed] [Google Scholar]
  • 7. ) Graham , S.Future inquiries into the epidemiology of gastric cancer . Cancer Res. , 35 , 3464 – 3468 ( 1975. ). [PubMed] [Google Scholar]
  • 8. ) Lilienfeld , D. E. , Garagliano , C. F. and Lilienfeld , A. M.Gastric cancer . J. Natl. Cancer Inst. , 57 , 9 ( 1976. ). [PubMed] [Google Scholar]
  • 9. ) Graham , S. , Lilienfeld , A. M. and Tidings , J. E.Dietary and purgation factors in the epidemiology of gastric cancer . Cancer , 20 , 2224 – 2234 ( 1967. ). [DOI] [PubMed] [Google Scholar]
  • 10. ) Hirayama , T.Epidemiology of stomach cancer . Gann Monogr. Cancer Res. , 11 , 3 – 19 ( 1971. ). [Google Scholar]
  • 11. ) Bjelke , E.Epidemiologic studies of cancer of the stomach, colon and rectum; with special emphasis on the role of diet . Scand. J. Gastroenterol. , 9 ( Suppl ), 1 – 235 ( 1974. ). [PubMed] [Google Scholar]
  • 12. ) Haenszel , W. , Kurihara , M. , Segi , M. and Lee , R. K. C.Stomach cancer among Japanese in Hawaii . J. Natl. Cancer Inst. , 49 , 969 – 988 ( 1972. ). [PubMed] [Google Scholar]
  • 13. ) Haenszel , W. , Kurihara , M. , Locke , F. B. , Shimizu , K. and Segi , M.Stomach cancer in Japan . J. Natl. Cancer Inst. , 56 , 265 – 278 ( 1976. ). [DOI] [PubMed] [Google Scholar]
  • 14. ) Correa , P. , Haenszel , W. , Cuello , C. , Tannenbaum , S. and Archer , M.A model for gastric cancer epidemiology . Lancet , ii , 58 – 60 ( 1975. ). [DOI] [PubMed] [Google Scholar]
  • 15. ) Raineri , R. and Weisburger , J. H.Reduction of gastric carcinogens with ascorbic acids . Ann. N.Y. Acad. Sci. , 258 , 181 – 189 ( 1975. ). [DOI] [PubMed] [Google Scholar]
  • 16. ) Tatematsu , M. , Takahashi , M. , Fukushima , S. , Hananouchi , M. and Shirai , T.Effects in rats of sodium chloride on experimental gastric cancers induced by N‐methyl‐N‐nitro‐N‐nitrosoguanidine or 4‐nitroquinoline‐l‐oxide . J. Natl. Cancer Inst. , 55 , 101 – 106 ( 1975. ). [DOI] [PubMed] [Google Scholar]
  • 17. ) Snedecor , G. W. and Cochran , W. G. “ Statistical Methods ” ( 1980. ). Iowa State Univ. Press; , Ames , Iowa . [Google Scholar]
  • 18. ) Breslow , N. E. and Day , N. E. “ Statistical Methods in Cancer Research , Vol. 1 . The Analysis of Case‐Control Studies ” ( 1980. ). IARC; , Lyon . [PubMed] [Google Scholar]
  • 19. ) SAS Institute . “ SAS User's Guide: Statistics , 1982 edition ” ( 1982. ). SAS Institute Inc. , Cary , NC . [Google Scholar]
  • 20. ) SAS Institute . “ SUGI Supplemental Library User's Guide , 1983 edition ” ( 1983. ). SAS Institute Inc. , Cary , NC . [Google Scholar]
  • 21. ) Byers , T. E. , Rosenthal , R. I. , Marshall , J. R. , Rzepka , T. F. , Cummings , K. M. and Graham , S.Dietary history from the distant past: a methodological study . Nutr. Cancer , 5 , 69 – 77 ( 1983. ). [DOI] [PubMed] [Google Scholar]
  • 22. ) Jensen , O. M. , Wahrendorf , J. , Rosenqvist , A. and Geser , A.The reliability of questionnaire‐derived historical dietary information and temporal stability of food habits in individuals . Am. J. Epidemiol. , 120 , 281 – 290 ( 1984. ). [DOI] [PubMed] [Google Scholar]
  • 23. ) Wynder , E. L. , Kmet , J. , Dungal , N. and Segi , M.An epidemiological investigation of gastric cancer . Cancer , 16 , 1461 – 1494 ( 1963. ). [DOI] [PubMed] [Google Scholar]
  • 24. ) Tajima , K. and Tominaga , S.Dietary habits and gastro‐intestinal cancers: a comparative case‐control study of stomach and large intestinal cancers in Nagoya, Japan . Jpn. J. Cancer Res. (Gann) , 76 , 705 – 716 ( 1985. ). [PubMed] [Google Scholar]
  • 25. ) Risch , H. A. , Jain , M. , Choi , N. W. , Fodor , J. G. , Pfeiffer , C. J. , Howe , G. R. , Harrison , L. W. , Craib , K. J. P. and Miller , A. B.Dietary factors and the incidence of cancer of the stomach . Am. J. Epidemiol. , 122 , 947 – 959 ( 1985. ). [DOI] [PubMed] [Google Scholar]
  • 26. ) Trichopoulos , D. , Ouranos , G. , Day , N. E. , Tzonou , A. , Manousos , O. , Papadimitriou , C. and Trichopoulos , A.Diet and cancer of the stomach: a case‐control study in Greece . Int. J. Cancer , 36 , 291 – 297 ( 1985. ). [PubMed] [Google Scholar]
  • 27. ) La Vecchia , C. , Negri , E. , Decarli , A. , D'Avanzo , B. and Franceschi , S.A case‐control study of diet and gastric cancer in northern Italy . Int. J. Cancer , 40 , 484 – 489 ( 1987. ). [DOI] [PubMed] [Google Scholar]
  • 28. ) U.S. Surgeon General . “ The Health Consequences of Smoking ,” pp. 132 – 137 ( 1982. ). U.S. Public Health Service; , Rockville . [Google Scholar]

Articles from Japanese Journal of Cancer Research : Gann are provided here courtesy of Wiley

RESOURCES