Abstract
A 10‐year‐old boy with chronic active Epstein‐Barr virus (EBV) infection developed T‐cell lymphoproliferation in the terminal stage of hepatic failure. The phenotypes of the proliferating lymphocytes were CD3±, CD4± and HLA‐DR±. The genomic DNAs from these cells demonstrated two rearranged T‐cell receptor μ‐chain genes and contained the EBV genome. These findings indicate that EBV can infect T lymphocytes and might cause clonal T‐cell lymphoproliferation.
Keywords: Epstein‐Barr virus, Chronic EB virus infection, Clonal lymphoproliferation, T lymphocyte
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