Abstract
The mutagenic compound, 2‐amino‐l‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (PhIP), originally isolated from cooked beef, was tested for carcinogenicity in CDF1 mice of both sexes. When PhIP was given in the diet at a concentration of 0.04%, high incidences and early appearances of lymphomas were observed in both sexes during the 579‐day experiment.
Keywords: Lymphoma, Mouse, PhIP
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