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. 1990 Aug;81(8):768–772. doi: 10.1111/j.1349-7006.1990.tb02643.x

Fv‐1 Restriction of Endogenous Feline C‐Type RD114 Virus Genome Phenotypically Mixed with Ecotropic Murine Leukemia Viruses

Kazuhiro Kakimi 1, Yoshiko Kishida 1, Ikuko Higuchi 1, Takahiro Kiyomasu 1, Hiroyuki Sakai 1, Riri Shibata 1, Shin‐ichiro Yanagawa 1, Akio Adachi 1, Akinori Ishimoto 1,✉
PMCID: PMC5918088  PMID: 2168865

Abstract

Endogenous feline leukemia RD114 virus genome rendered capable of infecting mouse cells by phenotypic mixing with an ecotropic murine leukemia virus (MuLV) exhibited the Fv‐1 restriction pattern of the ecotropic murine virus. However, RD114 genomes phenotypically mixed with ecotropic MuLV showed one‐hit dose‐response kinetics, even when titrated with murine cells with the restricted Fv‐1 phenotype.

Keywords: Murine leukemia virus, Feline C‐type RD114 virus, Fv‐1 gene

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