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. Author manuscript; available in PMC: 2018 Apr 27.
Published in final edited form as: Chemistry. 2015 Aug 18;21(39):13598–13608. doi: 10.1002/chem.201502211

Figure 1. Schematic representation of Hsp90 structure and its conformational equilibrium.

Figure 1

NTD, N-terminal Domain; MD, Middle Domain; CTD, C-terminal Domain; AS, predicted allosteric site; Aha1, Hsp90 co-chaperone; Sba1, yeast homologue of co-chaperone p23; Δ131Δ, Hsp90 client protein model.