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Japanese Journal of Cancer Research : Gann logoLink to Japanese Journal of Cancer Research : Gann
. 1996 Mar;87(3):317–323. doi: 10.1111/j.1349-7006.1996.tb00223.x

Usefulness of Ultrasonography Combined with Conventional Physical Examination in Mass Screening for Breast Cancer: A Retrospective Study of Yamanashi Health Care Center Results from 1989 to 1994

Hirotaka Okamoto 1,✉, Tadahiko Ogawara 1, Fumio Arihara 1, Kazuhisa Kobayashi 1, Shingo Inoue 2, Kaoru Nagahori 2, Masayuki Yamamoto 2, Takayoshi Sekikawa 2, Yoshiro Matsumoto 2
PMCID: PMC5921096  PMID: 8613436

Abstract

We retrospectively analyzed the records for 34,474 women who participated in mass screening for breast cancer by physical examination with or without ultrasonography (US) at Yamanashi Health Care Center between April, 1989 and March, 1994 to evaluate the usefulness of US in mass screening. In one group (15,935 women) conventional physical examination with inspection and palpation alone had been performed, and in another (18,539 women) both conventional physical and US examinations were performed. Breast cancer was detected in 27 of the women (0.08% of the total group screened), 22 of whom were in the group examined by US; moreover, 16 of these 22 women had early breast cancer, which was a non‐palpable tumor in 13. Half of the 22 women were examinees under the age of 50 years. Of the 22 tumors detected in the groups examined by US, 16 (73%) were early breast cancer. The overall detection of early breast cancer (0.09%) in the US group was significantly higher than that (0.01%) in the group examined by conventional methods (P < 0.05). Of the tumors detected in the US group, 59.1% were non‐palpable. These results suggest that early and non‐palpable breast cancer can be detected using US, and the incidence of detection of such tumors in women under the age 50 years is increased in mass screening including US examination. This examination is effective in mass screening for breast cancer, especially for early and non‐palpable breast cancer tumors.

Keywords: Breast cancer, Mass screening, Ultrasonography, Detection rate, Non‐palpable breast cancer

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REFERENCES

  • 1. ) Kuroishi , T. , Tominaga , S. and Hirose , K.Future prediction of breast cancer incidence and mortality in Japan . Jpn. J. Breast Cancer 5 , 367 – 373 ( 1990. ) ( in Japanese ). [Google Scholar]
  • 2. ) Shapiro , S.Evidence on screening for breast cancer from a randomized trial . Cancer 36 , 2772 – 2782 ( 1977. ). [DOI] [PubMed] [Google Scholar]
  • 3. ) Tabar , L. , Fagerberg , C. J. G. , Gad , A. , Baldetorp , R. , Holmberg , L. H. , Grontoft , O. , Ljungquist , U. , Lundstorm , B. , Manson , J. C. , Eklund , G. , Day , N. E. and Petterson , F. . Reduction in mortality from breast cancer after mass screening with mammography: randomized trial from the breast cancer screening working group of the Swedish National Board of Health and Welfare . Lancet , i , 829 – 832 ( 1985. ). [DOI] [PubMed] [Google Scholar]
  • 4. ) Andersson , I. , Aspegren , K. , Janzon , L. , Landberg , T. , Lindholm , T. , Linell , F. , Ljungberg , O. , Ranstam , J. and Sigfusson , B.Mammographic screening and mortality from breast cancer: the Malmo mammographic screening trial . Br. Med. J. 297 , 943 – 948 ( 1988. ). [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 5. ) Fletcher , W. S. , Black , W. , Harris , R. , Rimer , B. K. and Shapiro , S.Report of the international workshop on screening for breast cancer . J. Natl. Cancer Inst. 85 , 1644 – 1656 ( 1993. ). [DOI] [PubMed] [Google Scholar]
  • 6. ) Solin , L. J. , Legorreta , A. , Schultz , D. J. , Zatz , S. and Goodman , R. L.The importance of mammographic screening relative to the treatment of women with carcinoma of the breast . Arch. Intern. Med. 154 , 745 – 752 ( 1994. ). [PubMed] [Google Scholar]
  • 7. ) Frankl , G.The use of screening mammography . Cancer 60 , 1979 – 1983 ( 1987. ). [DOI] [PubMed] [Google Scholar]
  • 8. ) Morimoto , T. , Komaki , K. , Mori , T. , Sasa , M. , Ooshimo , K. , Miki , H. , Monden , Y. , Inui , K. , Saoyama , N. and Yoshida , H.The quality of mass screening for breast cancer by physical examination . Jpn. J. Surg. 23 , 200 – 204 ( 1993. ). [DOI] [PubMed] [Google Scholar]
  • 9. ) Noguchi , M. , Earashi , M. , Ohta , N. , Kitagawa , H. , Thomas , M. and Miyazaki , I.A comparison of breast cancers detected by mass screening and those found in outpatient clinics . Jpn. J. Surg. 23 , 325 – 330 ( 1993. ). [DOI] [PubMed] [Google Scholar]
  • 10. ) Ohuchi , N. , Yoshida , K. , Kimura , M. , Ouchi , A. , Kamioki , S. , Shiiba , K. , Matoba , N. , Kojima , S. , Takahashi , K. , Matsuno , S. , Fukao , A. , Abe , R. and Mori , S.Improved detection rate of early breast cancer in mass screening combined with mammography . Jpn. J. Cancer Res. 84 , 807 – 812 ( 1993. ). [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 11. ) Morimoto , T. , Sasa , M. , Yamaguchi , T. , Harada , K. and Sagawa , Y.High detection rate of breast cancer by mass screening using mammography in Japan . Jpn. J. Cancer Res. 85 , 1193 – 1195 ( 1994. ). [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 12. ) Gordon , P. B. and Goldenberg , S. L.Malignant breast masses detected only by ultrasound . Cancer 76 , 626 – 630 ( 1995. ). [DOI] [PubMed] [Google Scholar]
  • 13. ) Jackson , V. P. , Hendrick , R. E. , Feig , S. A. and Kopan , D. B.Imaging the radiographically dense breast . Radiology 188 , 297 – 301 ( 1993. ). [DOI] [PubMed] [Google Scholar]
  • 14. ) Bassett , L. W. and Kimme‐Smith , C.Breast sonography . Am. J. Roentgenol. 156 , 449 – 455 ( 1991. ). [DOI] [PubMed] [Google Scholar]
  • 15. ) Frazier , T. G. , Murphy , J. T. and Furlong , A.The selected use of ultrasound mammography to improve diagnostic accuracy in carcinoma of the breast . J. Surg. Oncol. 29 , 231 – 232 ( 1985. ). [DOI] [PubMed] [Google Scholar]
  • 16. ) Egan , R. L. and Egan , K. L.Automated water‐path full‐breast sonography . Am. J. Roentgenol. 143 , 499 – 507 ( 1984. ). [DOI] [PubMed] [Google Scholar]
  • 17. ) Tohnosu , N. , Okuyama , K. , Koide , Y. , Kikuchi , T. , Awano , T. , Matsubara , H. , Sano , T. , Nakaichi , H. , Funami , Y. , Matsushita , K. and Isono , K.A comparison between ultrasonography and mammography, computed tomography and digital subtraction angiography for the detection of breast cancers . Jpn. J. Surg. 23 , 704 – 710 ( 1993. ). [DOI] [PubMed] [Google Scholar]
  • 18. ) Japanese Breast Cancer Society . The general rules for clinical and pathological recording of breast cancer . Jpn. J. Surg. 19 , 612 – 632 ( 1989. ). [DOI] [PubMed] [Google Scholar]
  • 19. ) Kaluzny , A. D. , Rimer , B. and Harris , R.The national cancer institute and guideline development: lesson from the breast cancer screening controversy . J. Natl. Cancer Inst. 86 , 901 – 902 ( 1994. ). [DOI] [PubMed] [Google Scholar]
  • 20. ) Shapiro , S.Screening: assessment of current studies . Cancer 74 , 231 – 238 ( 1994. ). [DOI] [PubMed] [Google Scholar]
  • 21. ) Ota , J. , Horino , T. , Taguchi , T. , Ishida , T. , Izuo , M. , Ogita , M. , Abe , R. , Watanabe , H. , Morimoto , T. , Itoh , S. , Tashiro , H. , Yoshida , K. , Honda , K. , Sasakawa , M. , Enomoto , K. , Kashiki , Y. , Kido , C. , Kuroishi , T. and Tominaga , S.Mass screening for breast cancer: comparison of the clinical stages and prognosis of breast cancer detected by mass screening and in outpatient clinics . Jpn. J. Cancer Res. 80 , 1028 – 1034 ( 1989. ). [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 22. ) Morimoto , T. , Komaki , K. , Oshimo , K. , Yamakawa , T. , Mitsuyama , N. , Tanaka , T. and Monden , Y.Breast cancer detected by mass screening using physical examination alone . Jpn. J. Surg. 17 , 377 – 381 ( 1987. ). [DOI] [PubMed] [Google Scholar]
  • 23. ) Abe , R. , Kimura , M. , Sato , T. , Yoshida , K. , Hairu , T. , Kanno , H. , Takahashi , K. , Matoba , N. and Kumagai , N.Trial of early detection of breast cancer by mass screening . Cancer 56 , 1479 – 1483 ( 1985. ). [DOI] [PubMed] [Google Scholar]
  • 24. ) Japan Cancer Institute . The 8th Symp. Rec. Breast Cancer Screening , 19 – 21 ( 1990. ) ( in Japanese ).
  • 25. ) Morimoto , T. , Yamakawa , T. and Mitsuyama , N.Current problems in mass screening for breast cancer . Jpn. J. Cancer Chemother. 12 , 2273 – 2283 ( 1985. ) ( in Japanese with English abstract ). [PubMed] [Google Scholar]
  • 26. ) Berrino , F. , Bouchardy , C. and Sasco , A. J.Screening for breast cancer in pre‐menopausal women. Who should decide ? Int. J. Cancer 60 , 153 – 155 ( 1995. ). [DOI] [PubMed] [Google Scholar]
  • 27. ) Tominaga , S. and Kuroishi , T.Epidemiology of breast cancer in Japan . Breast Cancer 2 , 1 – 7 ( 1995. ). [DOI] [PubMed] [Google Scholar]
  • 28. ) Boyd , N. F. , Byng , J. W. , Jong , R. A. , Fishell , E. K. , Little , L. E. , Miller , A. B. , Lockwood , G. A. , Tritcher , D. L. and Yaffe , M. J.Quantitative classification of mammographic densities and breast cancer risk: results from the Canadian national breast screening study . J. Natl. Cancer Inst. 87 , 670 – 675 ( 1995. ). [DOI] [PubMed] [Google Scholar]

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