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. 1996 Aug;87(8):849–855. doi: 10.1111/j.1349-7006.1996.tb02110.x

Histologic Classification of Endoscopically Removed Flat Colorectal Polyps: A Multicentric Study

Carlos A Rubio 1,✉, Yo Kato 2, Teruyuki Hirota 3, Tetsuichiro Muto 4
PMCID: PMC5921179  PMID: 8797892

Abstract

A total of 594 flat colorectal polyps, removed at endoscopy, were histologically classified into non‐neoplastic (n=49) and neoplastic (n=545) polyps. Non‐neoplastic polyps were subdivided into metaplastic (n=45) and hyperplastic (n=4), whereas neoplastic polyps were subdivided into adenomas (n=481), intramucosal carcinomas (n=28) and invasive adenocarcinomas (n=36). Several adenoma phenotypes were discerned: tubular (n=375), serrated (n=59), villous (n=39), mixed (n=7) and fenestrated (n=1). Intramucosal carcinomas were subdivided into tubular (n=26) and serrated (n=2), and invasive adenocarcinomas into tubular (n=32), serrated (n=3) and fenestrated (n=1). The microscopic characteristics of each histologic phenotype described in this communication are defined and illustrated.

Keywords: Flat polyp, Colon, Classification, Histology

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