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. 2018 Mar 27;10(4):152. doi: 10.3390/v10040152

Figure 5.

Figure 5

R. rosea extract, ellagic acid and gallic acid inhibit EBOV infection at late entry step. Pseudotyped HIV/EOBV was incubated with A549 cells at 4 °C at the −1 h time point. After 1 h of incubation, the virus was removed and temperature was shifted to 37 °C to trigger virus internalization. (a) R. rosea extract (4 µg/mL), heparin (10 µg/mL), zidovudine (2 µM), CA-074 (100 µM) were introduced at different time points of virus infection, and the compounds’ effects on viral infection are shown (means ± SD (n = 3)); (b) R. rosea extract (4 µg/mL), gallic acid (30 µM), ellagic acid (30 µM), and benztropine (25 µM) were introduced at different time points of virus infection, and the compounds’ effects on viral infection are shown (means ± SD (n = 3)).