Table 1.
Patient data.
| Control | ||||||||
|---|---|---|---|---|---|---|---|---|
| Case no. | Age at surgery (yr) | Duration of seizures (yr) | MRI findings in hippocampus | Pathological diagnosis | Neuronal loss |
Watson grade | ||
| CA4 | CA1 | DG | ||||||
| E-1 | 15 | 10 | − | TS (T) | − | − | − | 0 |
| E-2 | 2 | 1 | − | FCD type II (T) | − | − | − | 0 |
| E-3 | 21 | 2 | − | Ependymoma (T) | − | − | − | 0 |
| E-4 | 20 | 7 | − | Ganglioglioma (T) | − | − | − | 0 |
| E-5 | 26 | 3 | − | No significant alterations | − | − | − | 0 |
| No-HS | ||||||||
| N-1 | 51 | 13 | − | No HS | − | − | − | 0 |
| N-2 | 12 | 6 | − | No HS | − | − | − | 1 |
| N-3 | 25 | 16 | − | No HS | − | − | − | 1 |
| N-4 | 33 | 12 | − | No HS, Polymicrogyria (T) | − | − | –, dis | 0 |
| N-5 | 19 | 2 | − | No HS | − | − | − | 1 |
| N-6 | 46 | 19 | − | No HS | − | − | − | 1 |
| HS | ||||||||
| S-1 | 32 | 19 | Atrophy | HS | +++ | +++ | +, dis | 4 |
| S-2 | 17 | 8 | Atrophy | HS, FCD type I (T) | +++ | +++ | +, dis | 4 |
| S-3 | 27 | 3 | Atrophy | HS | +++ | +++ | +, dis | 4 |
| S-4 | 37 | 22 | Atrophy | HS | +++ | +++ | ++, dis | 4 |
| S-5 | 32 | 5 | Atrophy | HS, FCD type I (T) | +++ | +++ | –, dis | 4 |
| S-6 | 53 | 43 | Atrophy | HS | +++ | +++ | ++, dis | 4 |
| S-7 | 64 | 44 | Atrophy | HS | +++ | +++ | –, dis | 4 |
| S-8 | 42 | 2 | Atrophy | HS, FCD type I (T) | +++ | +++ | +, dis | 4 |
| S-9 | 39 | 23 | Atrophy | HS, FCD type I (T) | +++ | +++ | +, dis | 4 |
| S-10 | 36 | 33 | Atrophy | HS, FCD type I (T) | +++ | +++ | +, dis | 4 |
| S-11 | 23 | 6 | Atrophy | HS, FCD type I (T) | +++ | +++ | +, dis | 4 |
| S-12 | 36 | 7 | Atrophy | HS, FCD type I (T) | +++ | +++ | –, dis | 4 |
| S-13 | 14 | 4 | Atrophy | HS | ++ | +++ | –, dis | 3 |
| S-14 | 27 | 16 | Atrophy | HS, FCD type I (T) | +++ | +++ | +, dis | 4 |
| S-15 | 43 | 34 | Atrophy | HS | +++ | +++ | +, dis | 4 |
| S-16 | 10 | 6 | Atrophy | HS, FCD type I (T) | +++ | +++ | +, dis | 4 |
| S-17 | 32 | 15 | Atrophy | HS, FCD type I (T) | ++ | +++ | +, dis | 3 |
| S-18 | 30 | 28 | Atrophy | HS | +++ | +++ | –, dis | 4 |
| S-19 | 52 | 17 | Atrophy | HS | +++ | +++ | +, dis | 4 |
| S-20 | 44 | 36 | Atrophy | HS, FCD type I (T) | ++ | +++ | –, dis | 3 |
HS: Hippocampal sclerosis, EFS: End folium sclerosis, (T): Temporal cortex, TS: Tuberous Sclerosis, FCD: Focal cortical dysplasia, dis: granule cell dispersion. +: mild, ++: moderate, +++: severe neuronal loss.