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- 1.Totani , T. , Aono , K. , Komura , M. . and Adachi , Y.Synthesis of (glycolato‐O, O')diammineplatinum (II) and its related complexes . Chem. Lett. , 3 , 429 – 432 ( 1986. ). [Google Scholar]
- 2.Suzumura , S. , Kato , T. , Ueda , R. . and Ohta , K.Effect of treatment schedule on antitumor activity of glycolato‐O, O' diammineplatinum (II), a new platinum derivative: comparison with cw‐diamminedichloroplatinum (II) . Anticancer Res. , 9 , 1083 – 1088 ( 1989. ). [PubMed] [Google Scholar]
- 3.Shiratori , O. , Kasai , H. , Uchida , N. , Takeda , Y. , Totani , T. . and Sato , K.Anti‐tumor activity of 254‐S, a platinum complex, in rodents . In “Recent Advances in Chemotherapy,” ed. Ishigami J. , pp . 635 – 636 ( 1985. ). University of Tokyo Press; , Tokyo . [Google Scholar]
- 4.Koenuma , M. , Kasai , H. , Uchida , N. , Wada , T. , Hattori , M. , Oguma , T. , Totani , T. . and Inaba , M.Pharmacokinetic correlation between experimental and clinical effects on human non‐small cell lung cancers of cis‐diammine glycolatoplatinum (254‐S) and cis‐diammine dichloroplatinum . Anticancer Res. , 15 , 417 – 422 ( 1995. ). [PubMed] [Google Scholar]
- 5.Kameyama , Y. , Okazaki , N. , Nakagawa , M. , Koshida , H. , Nakamura , M. . and Gemba , M.Nephrotoxicity of a new platinum compound, 254‐S, evaluated with rat kidney cortical slices . Toxicol. Lett. , 52 , 15 – 24 ( 1990. ). [DOI] [PubMed] [Google Scholar]
- 6.Furuse , K. , Fukuoka , M. , Ohshima , S. , Ariyoshi , Y. , Fujii , M. , Kurita , Y. , Hasegawa , K. , Homma , T. , Tamura , M. , Inoue , S. , Nishiwaki , Y. , Kimura , I. . and Niitani , H.Phase II clinical study of (glycolato‐O, O')diammineplatinum (II), a new platinum complex, for primary lung cancer . Proc. Am. Soc. Clin. Oncol. , 8 , 238 ( 1989. ). [Google Scholar]
- 7.Fukuda , M. , Shinkai , T. , Eguchi , K. , Sasaki , Y. , Tamura , T. , Ohe , Y. , Kojima , A. , Oshita , F. , Hara , K. . and Saijo , N.Phase II study of (glycolato‐O, O')diammineplatinum (II), a novel platinum complex, in the treatment of non‐small‐cell lung cancer . Cancer Chemother. Pharmacol. , 26 , 393 – 396 ( 1990. ). [DOI] [PubMed] [Google Scholar]
- 8.Inuyama , Y. , Miyake , H. , Horiuchi , M. , Hayasaki , K. , Komiyama , S. . and Ohta , K.An early phase II study of cis‐diammine glycolato platinum, 254‐S, for head and neck cancers . Jpn. J. Cancer Chemother. , 19 , 863 – 869 ( 1992. ). [PubMed] [Google Scholar]
- 9.Akaza , H. , Togashi , M. , Nishio , Y. , Miki , T. , Kotake , T. , Matumura , Y. , Yoshida , O. . and Aso , Y.Phase II study of cw‐diammine(glycolato)platinum, 254‐S, in patients with advanced germ‐cell testicular cancer, prostatic cancer, and transitional‐cell carcinoma of the urinary tract . Cancer Chemother. Pharmacol. , 31 , 187 – 192 ( 1992. ). [DOI] [PubMed] [Google Scholar]
- 10.Kato , T. , Noda , K. , Hirabayashi , K. . and Nishimura , H.Phase II study of cis‐diammine(glycolato)platinum (254‐S), a new platinum complex, for gynecological malignancy . Proc. 16th Int. Congr. Chemother., Anticancer Sect. , 823 , 1 – 2 ( 1989. ). [Google Scholar]
- 11.Uchida , N. , Kasai , H. , Takeda , Y. , Maekawa , R. , Sugita , K. . and Yoshioka , T.Augmented antitumor activity in combination chemotherapy of Nedaplatin with Etoposide . Anti-cancer Res. , 18 , 247 – 252 ( 1998. ). [PubMed] [Google Scholar]
- 12.Takeda , Y. , Kasai , H. , Uchida , N. , Yoshida , H. , Maekawa , R. , Sugita , K. . and Yoshioka , T.Enhanced antitumor efficacy of nedaplatin with 5‐fluorouracil against human squamous carcinoma xenografts . Anticancer Res. , 19 , 4059 – 4064 ( 1999. ). [PubMed] [Google Scholar]
- 13.Uchida , N. , Yoshida , H. , Yamada , H. , Wada , T. , Daikatsu , K. , Ikeuchi , I. , Maekawa , R. , Sugita , K. . and Yoshioka , T.Combination chemotherapy with nedaplatin and cyclophosphamide in human ovarian cancer model . Jpn. J. Cancer Res. , 90 , 887 – 894 ( 1999. ). [DOI] [PMC free article] [PubMed] [Google Scholar]
- 14.Braakhuis , B. J. , Guus , A. M. S. , van Dongen , G. A. , Vermorken , J. B. . and Snow , G. B.Preclinical in vivo activity of 2′,2′‐difluorodeoxycytidine (Gemcitabine) against human head and neck cancer . Cancer Res. , 51 , 211 – 214 ( 1991. ). [PubMed] [Google Scholar]
- 15.Noble , S. . and Goa , K. L.Gemcitabine. A review of its pharmacology and clinical potential in non‐small cell lung cancer and pancreatic cancer . Drugs , 54 , 447 – 472 ( 1997. ). [DOI] [PubMed] [Google Scholar]
- 16.Hui , Y. F. . and Reitz , J.Gemcitabine. A cytidine analogue active against solid tumors . Am. J. Health Syst. Pharm. , 54 , 162 – 170 ( 1997. ). [DOI] [PubMed] [Google Scholar]
- 17.Moore , D. F. , Pazdur , R. , Daugherty , K. , Tarassoff , P. . and Abbruzzese , J. L.Phase II study of gemcitabine in advanced colorectal adenocarcinoma . Invest. New Drugs , 10 , 323 – 325 ( 1992. ). [DOI] [PubMed] [Google Scholar]
- 18.Casper , E. S. , Green , M. R. , Kelsen , D. P. , Heelan , R. T. , Brown , T. D. , Flombaum , C. D. , Trochanowski , B. . and Tarassoff , P. G.Phase II trial of gemcitabine (2′,2′‐difluo‐rodeoxycytidine) in patients with adenocarcinoma of the pancreas . Invest. New Drugs , 12 , 29 – 34 ( 1994. ). [DOI] [PubMed] [Google Scholar]
- 19.Anderson , H. , Lund , B. , Bach , F. , Thatcher , N. , Walling , J. . and Hansen , H. H.Single‐agent activity of weekly gemcitabine in advanced non‐small‐cell lung cancer: a phase II study . J. Clin. Oncol. , 12 , 1821 – 1826 ( 1994. ). [DOI] [PubMed] [Google Scholar]
- 20.Cormier , Y. , Eisenhauer , E. , Muldal , A. , Gregg , R. , Ayoub , J. , Goss , G. , Stewart , D. , Tarasoff , P. . and Wong , D.Gemcitabine is an active new agent in previously untreated extensive small cell lung cancer (SCLC). A study of the National Cancer Institute of Canada Clinical Trials Group . Ann. Oncol. , 5 , 283 – 285 ( 1994. ). [DOI] [PubMed] [Google Scholar]
- 21.Lund , B. , Hansen , O. P. , Theilade , K. , Hansen , M. . and Neijt , J. P.Phase II study of gemcitabine (2′,2′‐difluorode‐oxycytidine) in previously treated ovarian cancer patients . J. Natl. Cancer Inst , 86 , 1530 – 1533 ( 1994. ). [DOI] [PubMed] [Google Scholar]
- 22.Michael , M. . and Moore , M.Clinical experience with gemcitabine in pancreatic carcinoma . Oncology , 11 , 1615 – 1622 ( 1997. ). [PubMed] [Google Scholar]
- 23.Bergman , A. M. , Ruiz van Haperen , V. W. T. , Veerman , G. , Huiper , M. . and Peters , G. J.Synergistic interaction between cisplatin and gemcitabine in vitro . Clin. Cancer Res. , 2 , 521 – 530 ( 1996. ). [PubMed] [Google Scholar]
- 24.van Moorsel , C. J. A. , Pinedo , H. M. , Veerman , G. , Bergman , A. M. , Kuiper , C. M. , Vermorken , J. B. , van der Vijgh , W. J. F. . and Peters , G. J.Mechanisms of synergism between cisplatin and gemcitabine in ovarian and non‐small‐cell lung cancer cell lines . Br. J. Cancer , 80 , 981 – 990 ( 1999. ). [DOI] [PMC free article] [PubMed] [Google Scholar]
- 25.Carmichael , J. , Allerheiligen , S. . and Walling , J.Phase I study of gemcitabine and cisplatin in non‐small cell lung cancer . Semin. Oncol , 23 , 55 – 59 ( 1996. ). [PubMed] [Google Scholar]
- 26.Crino , L. , Scagliotti , G. , Marangolo , M. , Figoli , F. , Clerici , M. , de Marinis , F. , Salvati , F. , Cruciani , G. , Dogliotti , L. , Pucci , F. , Paccagnella , A. , Adamo , V. , Altavilla , G. , Incoronato , P. , Trippetti , M. , Mosconi , A. M. , Santucci , A. , Sorbolini , S. , Oliva , C. . and Tonato , M.Cisplatin‐gemcita‐bine combination in advanced non‐small‐cell lung cancer: a phase II study . J. Clin. Oncol , 15 , 297 – 303 ( 1997. ). [DOI] [PubMed] [Google Scholar]
- 27.Mosconi , A. M. , Crino , L. . and Tonato , M.Combination therapy with gemcitabine in non‐small cell lung cancer . Eur. J. Cancer , 33 , S14 – S17 ( 1997. ). [DOI] [PubMed] [Google Scholar]
- 28.Anton , A. , Diaz‐Fernandez , N. , Gonzalez Larrba , J. L. , Vadell , C. , Masutti , B. , Montalar , J. , Barneto , L , Artal , A. . and Resell , R.Phase II trial assessing the combination of gemcitabine and cisplatin in advanced non‐small cell lung cancer (NSCLC) . Lung Cancer , 22 , 139 – 148 ( 1998. ). [DOI] [PubMed] [Google Scholar]
- 29.Cartei , G. , Sacco , C. , Sibau , A. , Pella , N. , Lop , A. . and Tabaro , G.Cisplatin and gemcitabine in non‐small‐cell lung cancer . Ann. Oncol , 10 , S57 – S62 ( 1999. ). [DOI] [PubMed] [Google Scholar]
- 30.Cardenal , F. , Lopex‐Cabrerizo , M. P. , Anton , A. , Alberola , V. , Massuti , B. , Carrato , A. , Barneto , L , Lomas , M. , Garcia , M. , Lianes , P. , Montalar , J. , Vandell , C. , Gonzalez‐Larriba , J. L. , Nguyen , B. , Artal , A. . and Rosell , R.Randomized phase HI study of gemcitabine‐cisplatin versus etoposide‐cisplatin‐etoposide in the treatment of locally advanced or metastatic non‐small‐cell lung cancer . J. Clin. Oncol. , 17 , 12 – 18 ( 1999. ). [DOI] [PubMed] [Google Scholar]
- 31.Langer , C. J. , Gandara , D. R. , Calvert , P. , Edelman , M. J. . and Ozols , R. F.Gemcitabine and carboplatin: an update of Phase I and II studies in non‐small cell lung cancer . Semin. Oncol. , 26 , 12 – 18 ( 1999. ). [PubMed] [Google Scholar]
- 32.Wallenstein , S. , Zucker , C. L. . and Fleis , J. L.Some statistical methods useful in circulation research . Circ. Res. , 47 , 1 – 9 ( 1980. ). [DOI] [PubMed] [Google Scholar]
- 33.Dunnett , C. W.New tables for multiple comparisons with a control . Biometrics , 20 , 482 – 491 ( 1964. ). [Google Scholar]
- 34.Braakhuis , B. J. M. , Ruiz van Haperen , V. W. T. , Welters , M. J. P. . and Peters , G. J.Schedule‐dependent therapeutic efficacy of the combination of gemcitabine and cisplatin in head and neck cancer xenografts . Chem. Eur. J. Cancer , 31A , 2335 – 2340 ( 1995. ). [DOI] [PubMed] [Google Scholar]
- 35.van Moorsel , C. J. A. , Pinedo , H. M. , Veerman , G. , Vermorken , J. B. , Postmus , P. E. . and Peters , G. J.Scheduling of gemcitabine and cisplatin in Lewis lung tumour bearing mice . Eur. J. Cancer , 35 , 808 – 814 ( 1999. ). [DOI] [PubMed] [Google Scholar]