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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Cytotherapy. 2015 Jul 22;17(10):1353–1364. doi: 10.1016/j.jcyt.2015.05.002

Table I.

Experimental versus PGE2-estimated TNF-α reduction by hMSCs.

Monolayer Encapsulated
PGE2 (ng/mL) 6.43 ± 0.74 8.30 ± 0.87
TNF-α (% maximum, experimental) 59 ± 7.4 13 ± 5.3
TNF-α (% maximum, estimated) 32 20

Experimental versus estimated values of rat TNF-α (percentage of maximum production) after treatment with monolayer or encapsulated hMSCs (1 × 105 cells/well). Estimated TNF-α values were calculated from a polynomial curve fit of TNF-α levels after exogenous PGE2 administration (Figure 4B), with use of the concentration of PGE2 detected in media collected from LPS-stimulated OHSC treated with hMSCs (Figure 2).