Table 1.
Clinical Parameter | Mean ± SD or n (%)
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Entire Cohort (n=51) |
CF (n=31) |
Pulmonary HTN (n=8) |
GVHD (n=7) |
Pulmonary Fibrosis (n=3) |
Other (n=2) |
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Gender | Female | 26 (51) | 18 (58) | 4 (50) | 1 (14) | 1 (33) | 1 (50) |
Male | 25 (49) | 13 (42) | 4 (50) | 6 (86) | 2 (67) | 1 (50) | |
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Age at transplant, y | 14.7 ± 4.8 | 15.7 ± 4.4 | 11.9 ± 5.5 | 16.2 ± 2.6 | 14.3 ± 4.8 | 5.6 ± 0.1 | |
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Race/Ethnicity | White | 36 (71) | 23 (74) | 4 (50) | 5 (71) | 3 (100) | 1 (50) |
Black | 2 (4) | 0 | 1 (12.5) | 1 (14) | 0 | 0 | |
Hispanic | 5 (10) | 3 (10) | 1 (12.5) | 1 (14) | 0 | 0 | |
Asian | 2 (4) | 0 | 1 (12.5) | 0 | 0 | 1 (50) | |
Other | 6 (12) | 5 (16) | 1 (12.5) | 0 | 0 | 0 | |
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FEV1, % predicted | 32 ± 11 | 35.8 ± 8.6 | — | 19.0 ± 7.3 | 20.5 ± 10.6 | — | |
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Height Z-score | −1.1 ± 1.4 | −1.1 ± 1.1 | 0.2 ± 1.3 | −2.0 ± 1.7 | −2.5 ± 0.7 | −3.2 ± 1.2 | |
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BMI Z-score | −0.8 ± 1.3 | −1.0 ± 1.1 | 0.4 ± 1.2 | −1.4 ± 1.2 | −0.8 ± 2.0 | −0.5 ± 0.2 | |
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Laboratory evaluation | 25(OH)D, ng/mL | 29.7 ± 12.6 | 31.7 ± 9.9 | 17.9 ± 6.8 | 39.3 ± 19.9 | 20.0 ± 15.5 | 23.4 ± 4.7 |
PTH, ng/mL | 37.2 ± 3.1 | 33.1 ± 19.0 | 81.0 ± 55 | 22.4 ± 34 | 27.8 ± 14 | 30 ± 4.9 | |
HbA1c, % | 6.3 ± 1.4 | 6.6 ± 1.5 | 5.4 | 5.4 ± 0.8 | 5.7 | — | |
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BMD Z-score | Lowest site | −2.2 ± 1.4 | −1.8 ± 1.1 | −1.2 ± 2.2 | −3.4 ± 2.2 | −2.9 ± 0.5 | −2.8 |
Spine | −1.6 ± 1.1 | −1.7 ± 1.1 | −1.0 ± 2.5 | −2.0 ± 1.0 | −1.4 | −2.2 | |
Hip | −1.8 ± 1.2 | −1.4 ± 0.8 | −1.0 ± 1.9 | −2.7 ± 2.6 | −2.9 ± 0.5 | −2.8 | |
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Patients with Fractures | Pre-transplant | 9 (18) | 4 (13) | 1 (12.5) | 2 (29) | 1 (33) | 1 (50) |
Post-transplant | 15 (29) | 9 (29) | 3 (37.5) | 1 (14) | 1 (33) | 1 (50) |