Table 3.
EO Components | Concentration of EOs Component (mM) | Change of GABA Current | Type of Receptor or Source of Receptor | Literature |
---|---|---|---|---|
(−)-Borneol | 0.3 | 350% | α1β2γ2s GABAA | [76] |
Camphor | 0.3 | 40% (inhibition) | α1β2γ2s GABAA | [76] |
Carvone | 0.3 | 115% | α1β2γ2s GABAA | [76] |
cis-Jasmone | 1 | 250% | Bovine GABAA | [79] |
Geraniol | 1 | 500% | α1β1GABAA | [79] |
(+)-Isomenthol | 1 | 327% | α1β2γ2s GABAA | [78] |
(+)-Isopulegol | 0.3 | 380% | α1β2γ2s GABAA | [78] |
Linalool | 1 | 350% | α1β1GABAA | [79] |
Nerolidol | 1 | 150% | α1β1GABAA | [79] |
Menthol | 0.32 | 200% | α1β2γ2s GABAA | [78] |
(+)-Menthol | 0.1 | 596% | α1β2γ2s GABAA | [76] |
(−)-Menthol | 0.3 | 600% | α1β2γ2s GABAA | [76] |
(−)-Menthone | 0.3 | 150% | α1β2γ2s GABAA | [76] |
Methyleugenol | 0.03 | 280% | hippocampal neurons | [80] |
Methyl jasmonate | 1 | 230% | Bovine GABAA | [79] |
α-Terpineol | 1 | 299% | α1β2γ2s GABAA | [78] |
α/β-Thujone | 0.3 | 40% (inhibition) | α1β2γ2s GABAA | [76] |
0.1 | 715% | Drosophila melanogaster homomeric RDLac GABAr | [76] | |
α-Thujone | 0.00066 | 208% | Rat GABAA | [81] |
0.003 | 70% (inhibition) | rat dorsal root ganglion neurons | [82] | |
Thymol | 0.1 | 416% | α1β3γ2s GABAA | [75] |
0.01 | 150% | α1β1γ2s GABAA | [75] |
Values in mg/mL were recalculated by the authors of this paper.