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. 2018 Apr 17;9(29):20409–20425. doi: 10.18632/oncotarget.24912

Table 2. Genes showing high level of CN alteration and corresponding values in TCGA.

CNAs DETECTED IN 37 CC TCGA
Gene symbol Chromosome
band
Number of
samples showing CNA
Percentage of samples showing CNA Log2
(CNA)*
Mean CN Ratio** Range of CN ratio Type of CNA Percentage of samples showing CN GAIN Number of
samples showing CN GAIN
Percentage of samples showing CN LOSS Number of
samples showing CN LOSS
CCND1 11q13.3 1 2.70 2.58 6 5.99–5.99 GAIN 41 11.45 51 14.25
CCNE1 19q12 1 2.70 2.03 4.09 4.09–4.09 GAIN 72 20.11 25 6.98
MAF 16q23.2 6 16.21 1.52 2.92 2.48–4.16 GAIN 84 23.46 23 6.42
BCL2L1 20q11.21 2 5.40 1.41 2.66 2.63–2.68 GAIN 254 70.95 0 0
SRC 20q11.23 2 5.40 1.39 2.92 1.62–4.21 GAIN 255 71.23 1 0.28
IRS2 13q34 1 2.70 1.35 2.55 2.54–2.54 GAIN 211 58.94 7 1.96
CEBPA 19q13.11 6 16.21 1.31 2.53 1.95–3.54 GAIN 69 19.27 25 6.98
PMS2 7p22.1 1 2.70 1.11 2.16 2.15–2.15 GAIN 195 54.47 1 0.28
FANCA 16q24.3 1 2.70 1.11 2.15 2.15–2.15 GAIN 85 23.74 27 7.54
CDK8 13q12.13 3 8.10 1.09 2.18 1.57–2.69 GAIN 214 59.78 8 2.23
CDKN2A 9p21.3 1 2.70 −2.13 0.23 0.22–0.22 LOSS 60 16.76 48 13.41
NPM1 5q35.1 1 2.70 −1.26 0.42 0.41–0.41 LOSS 24 6.7 67 18.72
TCL1A 14q32.13 1 2.70 −1.24 0.42 0.42–0.42 LOSS 25 6.98 118 32.96
CHEK2 22q12.1 1 2.70 −1.19 0.44 0.43–0.43 LOSS 9 2.51 117 32.68
PAX5 9p13.2 1 2.70 −1.17 0.45 0.44–0.44 LOSS 59 16.48 41 11.45
SUFU 10q24.32 1 2.70 −1.07 0.48 0.47–0.47 LOSS 12 3.35 80 22.35
HSP90AA1 14q32.31 1 2.70 −1.03 0.49 0.48–0.48 LOSS 24 6.7 118 32.96
FOXO3 6q21 3 8.10 −1 0.5 0.47–0.51 LOSS 51 14.25 49 13.69
NRAS 1p13.2 1 2.70 −0.99 0.5 0.50–0.50 LOSS 15 4.19 88 24.58
FBXW7 4q31.3 2 5.40 −0.94 0.52 0.49–0.55 LOSS 13 3.63 101 28.21

*Base 2 logarithm of CN ratio.

**Ratio of the Tumor Vs Normal intensity signal.