Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Feb 20;37(19):2532–2544. doi: 10.1038/s41388-018-0131-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, and provide a link to the Creative Commons license. You do not have permission under this license to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

PMC Copyright notice

Fig. 4 — Effects of HoxA9, HoxA10, and Mll-Ell on endogenous Triad1 mRNA and the 198 bp ARIH2 promoter construct are similar. a Triad1 expression increased in U937 cells expressing HoxA10 + HoxA9. Cells were transfected with vectors to express HoxA9, HoxA10, HoxA9 + HoxA10 or control. Triad1 mRNA expression was determined ± RA/DMF-differentiation. Significant differences indicated by *, **, ***, #, ##, ###, or &. b Triad1 expression increased in U937 cells expressing Mll-Ell, but this effect was decreased by constitutively active Shp2 (E76K). Cells were transfected with vectors to express Mll-Ell + E76K-Shp2 or control vector. Transfectants were analyzed ± RA/DMF. Significant differences indicated by *, **, ***, #, ##, or ###. c Expression of HoxA9 and HoxA10 is equivalent in Mll-Ell transfected U937 cells. Significant differences indicated by * or **. Not statistically significant differences indicated by ‘a’, ‘b’, or ‘c’. Bars in these graphs are means and error bars ± SEM