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Median concentration of Nestorone (NES) and estradiol (E2) observed for the main study cohort using contraceptive vaginal rings releasing 200 mcg NES with either 10, 20, or 40 mcg/day. Sampling occured twice weekly over the first 60 days of ring 1 and the last 30 days of ring 2. Breaks in lines indicates intervals of no data collection (days 61 – 83 and days 91 – 152).
