Supplementary Fig. 3.
MEG3 inhibits the cellular migration and invasion in vitro and in vivo. Representative image of the trans-well assay to investigate migration ability (A) and invasion ability (B) of SW1116 and LoVo cells with MEG3 over-expression or not. (C) Representative image of the trans-well assay to investigate migration ability (upper) and invasion ability (lower) of RKO cells with MEG3 down-regulaton or not. (D) Representative image of lung tissues from tumor metastasis mice model. Tumor modals indicated by arrows.