EQ-5D-5L (5L) is superior to EQ-5D-3L (3L) with respect to various measurement properties, enabling improvements in sensitivity and precision in health status measurement.

5L provides more precise measurements than 3L at individual and group levels, both in terms of responses to EQ-5D items and the resultant utilities.

3L systematically overestimates health problems when compared with 5L, leading to biased utilities.

5L is recommended for use across applications, including economic evaluation, clinical studies, quality of care and in public health studies.