Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Dec 26;9(1):231–247. doi: 10.1080/21505594.2017.1391447

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 1. — Neutralization of recombinant leukocidins by ASN-1 and ASN-2. A: Neutralization of recombinant HlgAB (10 nM), HlgCB (7.5 nM), LukED (10 nM) and LukSF-PV (5 nM) by ASN-1. B: Neutralization of LukGH (1 nM, TCH1516 LukGH) by ASN-2. C: left panel: Effect of individual toxins as in A, except for LukGH (1.875 nM each of the four LukGH variants expressed based on the MRSA252, MSHR1132, H19 and TCH1516 sequences) and a mixture thereof on PMN viability; right panel: Neutralization of a mixture of recombinant toxins by ASN-1, ASN-2 or ASN100 (1:1 mixture of ASN-1 and ASN-2). Antibody concentrations shown refer to individual mAbs. PMN viability was determined by luminescent quantification of cellular ATP levels. Data are derived from at least two independent experiments and shown as mean +/− SEM.