. 2017 Dec 26;9(1):231–247. doi: 10.1080/21505594.2017.1391447

Table 1.

S. aureus strains used in the study.

	MLST-SCCmec-spa-type or clonal complex	MRSA/MSSA	lukSF-PV	lukED	hlgABC	lukGH	hla	Source of strain
Prototype wild-type strains
TCH1516	ST8-IV-t622	MRSA	+	+	+	+	+	ATCC BAA-1717™
USA300 CA-MRSA	ST8-IV-t622	MRSA	+	+	+	+	+
NRS382	ST5-II-t002	MRSA	−	+	+	+	+	NARSA^a
USA100 HA-MRSA	ST5-II-t002	MRSA	−	+	+	+	+	NARSA^a
MRSA252	ST36-II-t018	MRSA	−	+	+	+	– ^**	ATCC BAA-1720™
USA200 European HA-MRSA	ST36-II-t018	MRSA	−	+	+	+	– ^**
NRS385	ST8-IV-t064	MRSA	−	+	+	+	+	NARSA^a
USA500 HA-MRSA	ST8-IV-t064	MRSA	−	+	+	+	+	NARSA^a
NRS386	ST72-IVa-t126	MRSA	+	+	+	+	+	NARSA^a
USA700 CA-MRSA	ST72-IVa-t126	MRSA	+	+	+	+	+	NARSA^a
MW2	ST1-IV-t125	MRSA	+	+	+	+	+	ATCC BAA-1707™
USA400	ST1-IV-t125	MRSA	+	+	+	+	+	ATCC BAA-1707™
Newman	ST254-t008	MSSA	−	+	+	+	+	Prof. Claire Poyart, Hôpital Cochin, Paris, France
H19Live-stock MRSA	CC10	MRSA	−	+	+	+	+	Prof. Ashley Robinson, University of Mississippi Medical Center, USA

Gene deletion mutant strains^b
TCH1516 Δhla/hlgABC/lukSF/lukED/lukGH or Δall toxin mutant	ST8-IV-t622	MRSA	−	−	−	−	−	In house^b
TCH1516ΔlukGH	ST8-IV-t622	MRSA	+	+	+	−	+	In house^b
TCH1516Δhla/hlgABC/lukSF/lukED or lukGH only	ST8-IV-t622	MRSA	−	−	−	+	−	In house^b
TCH1516Δhla	ST8-IV-t622	MRSA	+	+	+	+	−	In house^b
TCH1516ΔhlgABC/lukSF/lukED/lukGH or hla only	ST8-IV-t622	MRSA	−	−	−	−	+	In house^b
Human clinical isolates^c
LA#3	ST1970-t065	MSSA	−	−	+	+	+	Lahey Medical Center^c
LA#5	ST8-IV-t008	MRSA	−	+	+	+	+	Lahey Medical Center^c
LA#16	ST81-t127	MSSA	−	+	+	+	+	Lahey Medical Center^c
LA#45	ST121-t645	MSSA	−	+	+	+	+	Lahey Medical Center^c
LA#48	ST45-t040	MSSA	−	−	+	+	+	Lahey Medical Center^c
LA#66	ST5-II-t002	MRSA	−	+	+	+	+	Lahey Medical Center^c
LA#132	ST72-t148	MSSA	−	+	+	+	+	Lahey Medical Center^c
LA#164	ST188-t189	MSSA	−	+	+	+	+	Lahey Medical Center^c
LA#178	ST8-t334	MSSA	−	+	+	+	+	Lahey Medical Center^c
LA#186	ST5-II-t002	MRSA	−	+	+	+	+	Lahey Medical Center^c
LA#217	ST8-IV-t008	MRSA	+	+	+	+	+	Lahey Medical Center^c

Notes.

^**

mutated (early STOP codon).

Isolate was obtained through the Network on Antimicrobial Resistance in Staphylococcus Aureus (NARSA) program supported under NIAID/NIH contract HHSN272200700055C.

S. aureus isogenic mutant strain generated in house based on the TCH1516 BAA-1717™ background.

S. aureus isolates collected from ETA of ventilated patients. Stulik et al. AJRCCM, 2014.²⁸