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The Scientific World Journal logoLink to The Scientific World Journal
. 2004 Jul 20;4:531–535. doi: 10.1100/tsw.2004.111

Could Lipoprotein Lipase Play a Role in Alzheimer's Disease?

Jean-Francois Blain 1, Judes Poirier 1,2,*
PMCID: PMC5956492  PMID: 15311328

Abstract

This paper reviews recent literature on the role of lipoprotein lipase in the central nervous system with a focus on its recently described role in synaptic remodeling. This novel role could have implication for Alzheimer's disease treatment.

Keywords: lipoprotein lipase (LPL), cholesterol, lipids, Alzheimer’s disease (AD), synaptic remodeling, proteoglycans, amyloid


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