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. 2018 May 16;6:e4762. doi: 10.7717/peerj.4762

Table 1. Gene ontology analysis of UP group.

Category Term Count % P-Value Genes
GO TERM_BP GO:0042475∼odontogenesis of dentin-containing tooth 6 3.23 0.0003 Msx1, Nf2, Wnt6, Lhx8, Nkx2-3, Fgf4
GO TERM_BP GO:0014002∼astrocyte development 4 2.15 0.0004 Gfap, S100a8, S100a9, Pou3f2
GO TERM_BP GO:0044341∼sodium-dependent phosphate transport 3 1.61 0.0021 Slc17a3, Slc17a1, Slc17a2
GO TERM_BP GO:0046415∼urate metabolic process 3 1.61 0.0027 G6pc, Slc17a3, Slc17a1
GO TERM_BP GO:0021879∼forebrain neuron differentiation 3 1.61 0.0057 Lhx5, Lhx8, Phlda1
GO TERM_BP GO:0021846∼cell proliferation in forebrain 3 1.61 0.0086 Arx, Lhx5, Ncor2
GO TERM_BP GO:0014912∼negative regulation of smooth muscle cell migration 3 1.61 0.0097 Prkg1, Igfbp3, Trib1
GO TERM_BP GO:0035435∼phosphate ion transmembrane transport 3 1.61 0.0108 Slc17a3, Slc17a1, Slc17a2
GO TERM_BP GO:0030593∼neutrophil chemotaxis 4 2.15 0.0147 Gbf1, S100a8, S100a9, Vav1
GO TERM_BP GO:0023019∼signal transduction involved in regulation of gene expression 3 1.61 0.0174 Epcam, Tbx6, Msx1
GO TERM_BP GO:0070488∼neutrophil aggregation 2 1.08 0.0176 S100a8, S100a9
GO TERM_BP GO:0030317∼sperm motility 4 2.15 0.0207 Spag6l, Tekt2, Dnah1, Cacna1e
GO TERM_BP GO:0042593∼glucose homeostasis 5 2.69 0.0237 G6pc, Ffar1, Rph3al, Cacna1e, Ncor2
GO TERM_BP GO:0010273∼detoxification of copper ion 2 1.08 0.0349 Mt2a, Mt1
GO TERM_BP GO:0048863∼stem cell differentiation 3 1.61 0.0362 Epcam, Msx1, Ell3
GO TERM_BP GO:0002793∼positive regulation of peptide secretion 2 1.08 0.0434 S100a8, S100a9
GO TERM_BP GO:0035106∼operant conditioning 2 1.08 0.0434 Tacr2, Aldh1a7
GO TERM_BP GO:0010463∼mesenchymal cell proliferation 2 1.08 0.0434 Msx1, Fgf4
GO TERM_BP GO:0050714∼positive regulation of protein secretion 3 1.61 0.0487 Fgb, Rph3al, Exph5
GO TERM_CC GO:0005615∼extracellular space 19 10.22 0.0318 Wnt10a, Spaca3, Aifm2, S100a8, Pgf, S100a9, Cpxm2, Artn, Napsa, Tnfsf9, Muc4, Cxcl10, Serpina3n, Serpina6, Fgb, C1ql4, Wnt6, Igfbp3, Muc5b
GO TERM_MF GO:0005436∼sodium: phosphate symporter activity 3 1.61 0.0016 Slc17a3, Slc17a1, Slc17a2
GO TERM_MF GO:0015321∼sodium-dependent phosphate transmembrane transporter activity 3 1.61 0.0021 Slc17a3, Slc17a1, Slc17a2
GO TERM_MF GO:0001085∼RNA polymerase II transcription factor binding 4 2.15 0.0137 Gata1, Tbx6, Hcls1, Tead3
GO TERM_MF GO:0003779∼actin binding 7 3.76 0.0226 Spata32, Myrip, Nf2, Plekhh2, Map1a, Hcls1, Sptbn4
GO TERM_MF GO:0017137∼Rab GTPase binding 5 2.69 0.0250 Myrip, Rph3al, Exph5, Rgp1, Als2cl
GO TERM_MF GO:0043565∼sequence-specific DNA binding 11 5.91 0.0281 Arx, Gata1, Msx1, Thrb, Nkx6-2, Lhx5, Pou3f2, Prrx2, Lhx8, Ncor2, Nkx2-3
GO TERM_MF GO:0035662∼Toll-like receptor 4 binding 2 1.08 0.0346 S100a8, S100a9
GO TERM_MF GO:0004672∼protein kinase activity 7 3.76 0.0359 Stk26, Mos, Map3k10, Prkg1, Sik2, Epha1, Trib1