There is an error in Tables 2 and 3. The values “Mild to moderate” in the footnote "a" in the legends of Tables 2 and 3 are defined incorrectly. Please view the corrected tables here.
Table 2. Risk factors and adjusted hazard ratios of esophageal, stomach and colorectal cancers.
| Hazard ratio (95% CI)b | |||
|---|---|---|---|
| Covariate | Esophageal cancer | Stomach cancer | Colorectal cancer |
| Alcohol consumption a | |||
| Non | 1(reference) | 1(reference) | 1(reference) |
| Mild to moderate | 1.52 (1.45–1.60) | 1.05 (1.04–1.06) | 1.12 (1.10–1.13) |
| Heavy | 3.13 (2.95–3.32) | 1.24 (1.21–1.26) | 1.32 (1.30–1.35) |
| Smoking | |||
| Non | 1(reference) | 1(reference) | 1(reference) |
| Ex | 1.29 (1.21–1.37) | 1.22 (1.20–1.24) | 1.18 (1.16–1.20) |
| Current | 1.87 (1.77–1.98) | 1.34 (1.31–1.36) | 1.11(1.10–1.13) |
| Age (per 1y) | 1.10 (1.09–1.10) | 1.07 (1.07–1.07) | 1.06 (1.06–1.06) |
| Sex (male) | 0.15 (0.14–0.16) | 0.48 (0.48–0.49) | 0.77 (0.76–0.78) |
| Exercise (no) | 1.08 (1.03–1.14) | 1.06 (1.05–1.07) | 1.06 (1.05–1.07) |
| Lower quintile of yearly income (no) | 1.17 (1.12–1.23) | 1.01 (0.99–1.02) | 1.01 (1.00–1.02) |
| BMI (per 1Kg/m2) | 0.92 (0.92–0.93) | 1.00 (1.00–1.00) | 1.02 (1.01–1.02) |
| Diabetes mellitus (no) | 1.15 (1.09–1.21) | 1.17 (1.15–1.19) | 1.23 (1.21–1.24) |
BMI body mass index CI confidential interval y year
a Mild to moderate: < 30g alcohol/day; Heavy ≥30g alcohol/day
b adjusted for age, sex, exercise, income, BMI, diabetes mellitus, and smoking status.
Table 3. Subgroup analysis of the risk of esophageal, stomach and colorectal cancers according to alcohol consumption.
| Subgroups | Alcohol amounta | Hazard ratio (95% CI) b | ||
|---|---|---|---|---|
| Esophageal cancer | Stomach cancer | Colorectal cancer | ||
| Male | Non | 1 (reference) | 1(reference) | 1(reference) |
| Mild to moderate | 1.55 (1.47–1.63) | 1.06 (1.05–1.08) | 1.18 (1.16–1.20) | |
| Heavy | 3.17 (2.99–3.37) | 1.26 (1.24–1.29) | 1.40 (1.37–1.43) | |
| Female | Non | 1 (reference) | 1 (reference) | 1 (reference) |
| Mild to moderate | 1.16 (0.95–1.41) | 1.00 (0.97–1.02) | 0.98 (0.96–1.01) | |
| Heavy | 2.45 (1.50–4.03) | 1.06 (0.95–1.20) | 0.95 (0.87–1.04) | |
| BMI <18.5 | Non | 1.22 (1.06–1.41) | 0.90 (0.86–0.93) | 0.78 (0.75–0.82) |
| Mild to moderate | 2.55 (2.21–2.95) | 1.11 (1.05–1.18) | 1.03 (0.97–1.09) | |
| Heavy | 3.98 (3.28–4.83) | 1.47 (1.34–1.61) | 1.46 (1.32–1.61) | |
| BMI 18.5–22.9 | Non | 1 (reference) | 1 (reference) | 1 (reference) |
| Mild to moderate | 1.66 (1.54–1.78) | 1.08 (1.06–1.11) | 1.12 (1.10–1.14) | |
| Heavy | 3.57 (3.28–3.88) | 1.33 (1.29–1.37) | 1.38 (1.34.1.43) | |
| BMI 23.0–24.9 | Non | 0.80 (0.74–0.88) | 1.03 (1.01–1.05) | 1.06 (1.04–1.08) |
| Mild to moderate | 1.11 (1.02–1.21) | 1.06 (1.04–1.09) | 1.18 (1.16–1.21) | |
| Heavy | 2.46 (2.22–2.74) | 1.25 (1.20–1.29) | 1.38 (1.33–1.43) | |
| BMI 25.0–29.9 | Non | 0.78 (0.72–0.86) | 1.04 (1.02–1.06) | 1.10 (1.08–1.11) |
| Mild to moderate | 1.03 (0.94–1.12) | 1.07 (1.04–1.09) | 1.23 (1.20–1.25) | |
| Heavy | 1.93 (1.73–2.14) | 1.20 (1.17–1.24) | 1.40 (1.36–1.45) | |
| BMI≥30.0 | Non | 0.66 (0.51–0.85) | 1.07 (1.02–1.11) | 1.13 (1.09–1.17) |
| Mild to moderate | 0.74 (0.55–0.99) | 1.03 (0.97–1.09) | 1.23 (1.17–1.30) | |
| Heavy | 1.19 (0.81–1.75) | 1.11 (1.01–1.22) | 1.23 (1.12–1.35) | |
| Non | Non | 1 (reference) | 1 (reference) | 1 (reference) |
| smoker | Mild to moderate | 1.43 (1.31–1.56) | 1.07 (1.05–1.09) | 1.12 (1.10–1.14) |
| Heavy | 3.64 (3.25–4.08) | 1.35 (1.29–1.40) | 1.44 (1.38–1.49) | |
| Ex | Non | 1.30 (1.18–1.42) | 1.24 (1.22-.1.27) | 1.19 (1.17–1.22) |
| smoker | Mild to moderate | 1.95 (1.79–2.12) | 1.30(1.27–1.33) | 1.34 (1.31–1.36) |
| Heavy | 4.11 (3.70–4.55) | 1.46 (1.41–1.51) | 1.56 (1.51–1.61) | |
| Current | Non | 1.87 (1.71–2.04) | 1.38 (1.35–1.41) | 1.14 (1.12–1.17) |
| smoker | Mild to moderate | 2.96 (2.74–3.20) | 1.40 (1.37–1.43) | 1.25 (1.23–1.28) |
| Heavy | 5.58 (5.14–6.06)) | 1.66 (1.62–1.71) | 1.44 (1.40–1.48) | |
a Mild to moderate: < 30g alcohol/day; Heavy ≥30g alcohol/day
b Adjusted for age, sex, regular exercise, yearly income, diabetes mellitus and, smoking status.
Reference
- 1.Choi YJ, Lee DH, Han K-D, Kim HS, Yoon H, Shin CM, et al. (2017) The relationship between drinking alcohol and esophageal, gastric or colorectal cancer: A nationwide population-based cohort study of South Korea. PLoS ONE 12(10): e0185778 https://doi.org/10.1371/journal.pone.0185778 [DOI] [PMC free article] [PubMed] [Google Scholar]
