Figure 1.

Preliminary research on the role of the genes 0350, nox, tpx and copA in oxidative stress tolerance and virulence of S. suis 2. A, Growth curves of S. suis strains cultured under static conditions, i.e. low-oxygen conditions. B, Growth curves of S. suis strains cultured in a shaking incubator set to 200 rpm, i.e. high-oxygen conditions. C, Growth curves of S. suis strains cultured with 0.5 mM H₂O₂ under static conditions. Growth curves shown are representative of at least 3 independent experiments. D, Survival curves of mice infected with S. suis strains. Significant difference was observed between the WT and Δnox group (P = 0.0004, the log-rank test).