Table 2. Primary information and minor allele frequencies (MAFs) of selected SNPs.
| SNPs | Gene | Chr | Location | Base change | MAFa in dbSNP database (CHB) | MAF in our controls | HWEa | Genotyping rate (%) | Pb |
|---|---|---|---|---|---|---|---|---|---|
| rs217727 | H19 | 11p15.5 | exon | C>T | 0.354 | 0.289 | 0.163 | 99.1 | 0.002 |
| rs2839701 | H19 | 11p15.5 | exon | C>G | 0.308 | 0.281 | 0.752 | 100 | 0.019 |
| rs2067051 | H19 | 11p15.5 | exon | G>A | 0.244 | 0.273 | 0.630 | 99.1 | 0.144 |
| rs2251375 | H19 | 11p15.5 | intron | C>A | 0.458 | 0.424 | 0.134 | 100 | 0.702 |
aHWE = Hardy-Weinberg equilibrium. MAF = minor allele frequency.
bDerived from logistic regression with an adjustment for age, sex, smoking and drinking status inadditive model.