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Endocrine-disrupting chemicals increase mitogenic signaling. Western immunoblot analysis of SUM149 cells treated for 30 min with indicated doses of BPA, HPTE, methoxychlor, esfenvalerate, chlorothalonil and niclosamide. Blots probed for pEGFR, EGFR, pERK and ERK expression, with GAPDH used as a loading control. Numbers represent fold change of phospho to total protein (EGFR or ERK) normalized to untreated.
