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. 2018 May 11;9(36):24457–24469. doi: 10.18632/oncotarget.25326

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Copyright: © 2018 Shindo et al.

This article is distributed under the terms of the Creative Commons Attribution License (CC-BY), which permits unrestricted use and redistribution provided that the original author and source are credited.

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(A) Anti-tumor effects of CDDP in T24 and T24RC cells. Numbers of cells treated with the indicated concentrations of CDDP are shown relative to those without treatment. (B) qRT-PCR analysis of miR-200b in T24 and T24RC cells. (C) Effects of miR-200b on CDDP sensitivity in T24RC cells. Numbers of cells transfected with a miR-200b mimic or negative control (NC) and then treated with the indicated concentrations of CDDP are shown relative to cells without treatment. (D) Effects of miR-200b inhibition on CDDP sensitivity in T24 cells. Cells were transfected with a miR-200b inhibitor or negative control (NC) and then treated with the indicated concentrations of CDDP. (E) Anti-tumor effects of the indicated concentrations of CDDP on EJ138 and EJ138RC cells. (F) qRT-PCR analysis of miR-200b in EJ138 and EJ138RC cells. Shown are means of 6 (A, C–E) or 3 (B, F) replications; error bars represent SDs. ^*P < 0.05, ^**P < 0.01.