Figure 5. Effect of HX-1171 on insulin secretion by STZ-treated cells.

Insulin secretion was measured by ELISA. (A) INS-1 cells were either untreated or treated with STZ (5 mM) and HX-1171 (10 μM) for the indicated times, and (B) the cells were treated with the indicated dose of STZ and HX-1171 for 2 hrs. Data are presented as mean ± SD (n = 4). ^**P < 0.005, ^***P < 0.001 compared to the control group, ^#P < 0.05, ^##P < 0.005, ^###P < 0.001 compared to the STZ group.