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. 2018 Mar 9;37(21):2873–2889. doi: 10.1038/s41388-018-0183-6

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — MiR-23a enhances HUVEC proliferation, migration, and tube formation. a Transfection efficiency was measured by qRT-PCR. One-way ANOVA. b The cell growth of transfected HUVECs was measured by CCK8 assay. Two-way ANOVA. c, d Flow cytometry analysis of the cell cycle was performed at 36 h after transfection. The graph summarizes the results of three independent experiments. One-way ANOVA. e, f Wound-healing assay showed cell migration in transfected HUVECs. Two-way ANOVA. g, h Transwell migration assays were performed to measure cell migration. Cell numbers were calculated as the average of 10 randomly picked fields. One-way ANOVA. i HUVECs were inoculated in Matrigel and the indicated images were captured. j, k Analyses of p-ERK expression in transfected cells