Table 4.
Sex, cardiovascular disease (CVD) status and positive attitudes associated with participation in clinical trials
| Relative risk (95% CI) | Relative risk (95% CI) | |||||
|---|---|---|---|---|---|---|
| Attitudea | Women | Men | P value | Non-CVD | CVD | P value |
| Random | 1 [Reference] | 0.98 (0.88–1.10) | .79 | 1 [Reference] | 1.03 (0.92–1.16) | .58 |
| Blinded | 1 [Reference] | 0.99 (0.89–1.20) | .85 | 1 [Reference] | 1.05 (0.94–1.17) | .35 |
| Side effects | 1 [Reference] | 1.02 (0.79–1.32) | .87 | 1 [Reference] | 0.81 (0.63–1.05) | .11 |
| Conflict of interest | 1 [Reference] | 1.00 (0.74–1.36) | .99 | 1 [Reference] | 0.92 (0.67–1.25) | .57 |
| Guinea pigs (reversed) b | 1 [Reference] | 0.84 (0.73–0.98) | .02 | 1 [Reference] | 1.02 (0.88–1.84) | .79 |
| Talking to physician | 1 [Reference] | 0.95 (0.87–1.04) | .25 | 1 [Reference] | 1.00 (0.91–1.09) | .92 |
| Terminally ill (reversed)b | 1 [Reference] | 0.93 (0.86–1.00) | .05 | 1 [Reference] | 0.98 (0.91–1.05) | .57 |
| Experimental treatments | 1 [Reference] | 0.85 (0.61–1.19) | .35 | 1 [Reference] | 0.84 (0.59–1.19) | .33 |
aAdjusted for age, marital status, race, education, income and current health status
bDisagreement with questionnaire prompt