Table 1. GRADE score-quality interpretation.

GRADE: Grading of Recommendations Assessment, Development and Evaluation

GRADE Score	Quality	Interpretation
≤1	Very low	Any estimate of effect is highly uncertain
2	Low	Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate
3	Moderate	Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate
≥ 4	High	Further research is very unlikely to change our confidence in the estimate of effect