Table 4.
Gastro-intestinal permeability during AE-COPD compared to stable condition (n = 17)
| Visit 1 | Visit 2 | p value* | |
|---|---|---|---|
| Lactulose | 29.1 (16.9–43.8) | 20.3 (10.8–48.8) | 0.332 |
| L-Rhamnose | 795.8 (400.3–1,061.1) | 566.5 (383–1,679) | 0.586 |
| Erythritol | 10,454 (6,014–13,242) | 5,549 (3,768–14,491) | 0.266 |
| Sucrose | 50.4 (32.6–122.7) | 75.7 (22.2–122.3) | 0.687 |
| Sucralose | 104.5 (55.9–187.2) | 66.5 (27.4–222.3) | 0.227 |
| L/R ratio, ×103 | 40.9 (29.4–49.6) | 27.3 (19.5–47.7) | 0.039 |
| S/E ratio, ×103 | 11.2 (8.2–16.8) | 10.5 (8.8–16.7) (n = 16) | 1.00 |
| Su/R ratio, ×103 | 77.7 (44.0–159.7) | 86.2 (42.1–190.6) | 0.906 |
Data are presented as medians and 25–75% percentiles. The table shows the sugar urinary excretion levels after drinking a sugar solution measured during both visits (conditions). AE-COPD, acute exacerbation of chronic obstructive pulmonary disease; L/R ratio, ratio between lactose and L-rhamnose; S/E ratio, ratio between sucralose and erythritol; Su/R ratio, ratio between sucrose and rhamnose.
*
Wilcoxon signed-rank test.