Figure 2. Substrate preference for attachment of the IC head group in biosynthesis of IC-ascarosides.
(A) Possible attachment of the IC group to ascarosides with different side-chain lengths (C5–C13). (B) Percent conversion of each ascaroside to the corresponding IC-ascaroside by daf-22(m130) worms. Data represent the mean ± SD of three independent experiments.