Table 1.
Group | % ± SEM | # | Location* | ||
---|---|---|---|---|---|
synapse | membrane | cytoplasm | |||
CA1 | |||||
Ctl males | 1 ± 0.6 | 3 | 0 | 0 | 3 |
CIS males | 3 ± 0.6 | 9 | 1 | 3 | 5 |
Ctl females | 3.3 ± 1.2 | 10 | 0 | 4 | 6 |
CIS females | 1.7 ± 0.3 | 5 | 1 | 1 | 3 |
CA3 | |||||
Ctl males | 2.5 ± 1.0 | 10 | 1 | 5 | 5 |
CIS males | 4.8 ± 1.0 | 17 | 0 | 5 | 12 |
Ctl females | 2.1 ± 0.3 | 9 | 2 | 3 | 4 |
CIS females | 2.3 ± 0.8 | 9 | 4 | 2 | 3 |
Some spines had more than one CRFR1-SIG particle. CA1: percentage of CRFR1-labeled spines determined from 100 randomly selected spines per rat. CA3: percentage of spines determined from dendritic spines contacted by 50 randomly selected mossy fiber terminals per rat. N = 3 rats per condition.