Table 2. Relationships between clinicopathological features of ESCC and the expression of AE2.
| Variable | AE2 staining score in WT | p value | AE2 staining score at the IF | p value | ||
|---|---|---|---|---|---|---|
| High | Low | High | Low | |||
| (n = 31) | (n = 30) | (n = 35) | (n = 26) | |||
| Gender | ||||||
| Male | 25 | 27 | 0.4729 | 27 | 25 | 0.0653 |
| Female | 6 | 3 | 8 | 1 | ||
| Age | ||||||
| <65 years | 16 | 21 | 0.1919 | 21 | 16 | 1.0000 |
| ≥65 years | 15 | 9 | 14 | 10 | ||
| Tumor size | ||||||
| <50 mm | 22 | 18 | 0.4263 | 24 | 16 | 0.5963 |
| ≥50 mm | 9 | 12 | 11 | 10 | ||
| Histological type | ||||||
| Well-/moderately differentiated SCC | 21 | 23 | 0.5700 | 23 | 21 | 0.2536 |
| Poorly differentiated SCC | 10 | 7 | 12 | 5 | ||
| Lymphatic invasion | ||||||
| Negative | 11 | 17 | 0.1261 | 14 | 14 | 0.3107 |
| Positive | 20 | 13 | 21 | 12 | ||
| Venous invasion | ||||||
| Negative | 16 | 20 | 0.3004 | 18 | 18 | 01952 |
| Positive | 15 | 10 | 17 | 8 | ||
| pT | ||||||
| pT1 | 17 | 10 | 0.1236 | 20 | 7 | 0.0221* |
| pT2-3 | 14 | 20 | 15 | 19 | ||
| pN | ||||||
| pN0 | 14 | 13 | 1.0000 | 16 | 11 | 1.0000 |
| pN1-3 | 17 | 17 | 19 | 15 | ||
| pStage | ||||||
| pStage 0–I | 9 | 8 | 1.0000 | 10 | 7 | 1.0000 |
| pStage II–IV | 22 | 22 | 25 | 19 | ||
SCC: squamous cell carcinoma; pT: pathological T stage; pN: pathological N stage; pStage: pathological stage.
*p < 0.05: Fisher's exact test.