Table 2. Percentage of apoptosis and proliferation of the cytokine combinations tested in 12 CLL.
Cytokine | % Apoptosis | % Proliferation |
---|---|---|
Medium | 18 ± 17 | 2 ± 1 |
Medium+CLL NE | 17 ± 14 | 2 ± 1 |
Medium+HS5 | 27 ± 17 | 2 ± 2 |
Medium+CLL NE+HS5 | 21 ± 15 | 2 ± 3 |
CD40L+CpG | 17 ± 14 | 6 ± 8 |
CD40L+CpG+Ig | 23 ± 14 | 5 ± 7 |
CD40L+CpG+BAFF | 19 ± 13 | 7 ± 8 |
CD40L+CpG+IL21 | 49 ± 19 | 6 ± 11 |
CD40L+CpG+HS5 | 30 ± 19 | 5 ± 13 |
CD40L+CpG+Ig+HS5 | 36 ± 20 | 4 ± 12 |
CD40L+CpG+BAFF+HS5 | 39 ± 22 | 6 ± 12 |
CD40L+CpG+IL21+HS5 | 62 ± 20 | 10 ± 18 |
CD40L+IL21 | 48 ± 14 | 3 ± 3 |
CD40L+IL21+Ig | 51 ± 15 | 2 ± 1 |
CD40L+IL21+BAFF | 52 ± 19 | 2 ± 4 |
CD40L+IL21+HS5 | 61 ± 16 | 3 ± 3 |
CD40L+IL21+Ig+HS5 | 62 ± 15 | 4 ± 4 |
CD40L+IL21+BAFF+HS5 | 64 ± 19 | 3 ± 3 |
CpG+IL2 | 16 ± 18 | 18 ± 24 |
CpG+IL2+CD40L | 16 ± 17 | 13 ± 19 |
CpG+IL2+Ig | 25 ± 19 | 19 ± 22 |
CpG+IL2+BAFF | 25 ± 18 | 19 ± 22 |
CpG+IL2+HS5 | 30 ± 19 | 30 ± 27 |
CpG+IL2+CD40L+HS5 | 33 ± 23 | 14 ± 17 |
CpG+IL2+Ig+HS5 | 38 ± 24 | 23 ± 25 |
CpG+IL2+BAFF+HS5 | 36 ± 22 | 20 ± 25 |
Data from apoptosis are subtracted from the value of apoptosis after thaw. Results are represented as median ± SD (N = 12).