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. 2018 May 25;9(40):26019–26031. doi: 10.18632/oncotarget.25419

Table 2. Percentage of apoptosis and proliferation of the cytokine combinations tested in 12 CLL.

Cytokine % Apoptosis % Proliferation
Medium 18 ± 17 2 ± 1
Medium+CLL NE 17 ± 14 2 ± 1
Medium+HS5 27 ± 17 2 ± 2
Medium+CLL NE+HS5 21 ± 15 2 ± 3
CD40L+CpG 17 ± 14 6 ± 8
CD40L+CpG+Ig 23 ± 14 5 ± 7
CD40L+CpG+BAFF 19 ± 13 7 ± 8
CD40L+CpG+IL21 49 ± 19 6 ± 11
CD40L+CpG+HS5 30 ± 19 5 ± 13
CD40L+CpG+Ig+HS5 36 ± 20 4 ± 12
CD40L+CpG+BAFF+HS5 39 ± 22 6 ± 12
CD40L+CpG+IL21+HS5 62 ± 20 10 ± 18
CD40L+IL21 48 ± 14 3 ± 3
CD40L+IL21+Ig 51 ± 15 2 ± 1
CD40L+IL21+BAFF 52 ± 19 2 ± 4
CD40L+IL21+HS5 61 ± 16 3 ± 3
CD40L+IL21+Ig+HS5 62 ± 15 4 ± 4
CD40L+IL21+BAFF+HS5 64 ± 19 3 ± 3
CpG+IL2 16 ± 18 18 ± 24
CpG+IL2+CD40L 16 ± 17 13 ± 19
CpG+IL2+Ig 25 ± 19 19 ± 22
CpG+IL2+BAFF 25 ± 18 19 ± 22
CpG+IL2+HS5 30 ± 19 30 ± 27
CpG+IL2+CD40L+HS5 33 ± 23 14 ± 17
CpG+IL2+Ig+HS5 38 ± 24 23 ± 25
CpG+IL2+BAFF+HS5 36 ± 22 20 ± 25

Data from apoptosis are subtracted from the value of apoptosis after thaw. Results are represented as median ± SD (N = 12).