Table 2.

Distribution of methylation levels (percent) in 29 genes by breast cancer family history (BCFH) in the LEGACY Girls Study.

	BCFH+			BCFH-
		% Methylation			% Methylation
Amplicon	No.	Median	IQR	No.	Median	IQR	P value
ADRB1	171	23.0	8.9	142	24.9	10.4	0.125
ARHGEF7	160	36.6	12.6	124	37.1	17.2	0.728
BRCA1	198	83.5	12.7	160	83.3	13.9	0.648
CCDC85A	198	36.6	11.0	157	35.9	11.9	0.463
CCNL1	166	0.1	0.2	131	0.1	0.4	0.799
CDH1	201	5.9	2.7	163	6.1	2.8	0.612
CELF4	198	54.3	15.5	150	51.9	13.5	0.06
Chr 11	169	9.4	11.8	125	9.0	10.4	0.881
Chr 12	201	78.0	6.1	156	77.5	8.2	0.265
Chr 16	209	81.9	11.9	165	81.7	13.2	0.597
Chr 4	161	86.0	14.4	139	85.7	14.6	0.673
CYP1A1	177	44.4	26.9	139	43.4	27.0	0.178
DLGAP2	199	97.2	1.6	163	97.2	1.4	0.498
ESR1	196	55.0	21.6	161	49.2	25.2	0.003
GAB2	168	98.7	3.7	136	99.0	3.2	0.398
GNA12	138	31.6	43.8	105	34.7	32.8	0.646
MCHR2	210	11.2	5.8	165	11.1	5.4	0.98
OBSCN	182	94.2	3.7	148	94.1	3.6	0.696
PCDHGB1	215	38.0	11.0	171	38.8	11.5	0.447
PEX14	191	70.6	14.4	152	72.9	14.8	0.09
RAD23B	134	97.7	2.3	119	98.1	2.5	0.407
RAD51L1	130	98.3	3.6	97	98.7	3.2	0.896
SEC16B	153	75.1	18.9	119	72.8	16.8	0.026
SLC39A14	199	88.4	13.6	162	90.3	11.8	0.238
TCF7L2	169	42.7	29.6	143	45.4	27.9	0.671
TERT	176	97.6	3.8	142	97.8	3.6	0.713
XRCC3	186	78.4	7.2	143	78.7	7.8	0.691
ZFPM2	192	64.5	26.1	152	65.6	20.0	0.088
ZNF483	201	36.3	6.5	157	37.4	7.3	0.384