Fig. 6.

Modulation of gut microbiota can effectively attenuate bowel motility and intracolonic SLCFAs production in NMS rats based on 14 consecutive days of neomycin treatment (150 mg/kg). a Accumulation of fecal pellets within 60 min before and after neomycin treatment. b The gut transit time in rats with or without intervention. c Relative levels of SLCFA-producing genera normalized with 16s rRNA level. d Relative levels of SLCFA-synthetic genes among three groups. e The amounts of individual SLCFAs per gram colonic contents in rats from three groups. Values for line/bar charts are expressed as mean ± SEM, for box plots are presented as interquartile range. Statistics among three groups was calculated by One-way ANOVA. Significance compared with control group is defined as *p < 0.05; **p < 0.01; ***p < 0.005, compared with NMS group is described as #p < 0.05; ##p < 0.01; ###p < 0.005